Homa-IR
Homeostatic Model Assessment for Insulin Resistance
In short
The Homeostatic Model Assessment (HOMA) is a method used to quantify insulin resistance and beta-cell function. It is based on a mathematical level that considers the concentration of glucose and insulin during fasting.
The normal range (for a normal non-insulin resistent person) is: 0,23 - 2.5
Calculator
| HOMA-IR | Interpretation |
|---|---|
| ≤ 2,5 | Normal (no insulin resistance) |
| 2,6 – 5,0 | Insulin resistance |
| > 5,0 | Marked insulin resistance |
Related tools
Frequently asked questions
What are the normal HOMA Index values?
In people without insulin resistance the HOMA Index is generally between 0.23 and 2.5. Values above 2.5 may indicate reduced insulin sensitivity. Reference values can vary depending on the laboratory and the population considered.
How is HOMA-IR calculated?
HOMA-IR is derived from fasting glucose and insulin. With glucose in mg/dL: HOMA-IR = (glucose × insulin) / 405. With glucose in mmol/L: HOMA-IR = (glucose × insulin) / 22.5.
What does a high HOMA-IR mean?
A high value suggests insulin resistance, a condition in which insulin is less effective at moving glucose into the cells. It should always be interpreted by a doctor together with the other tests.
What is HOMA-B%?
HOMA-B% estimates the function of the pancreatic beta cells, i.e. their ability to produce insulin, again from fasting glucose and insulin values.
Does the HOMA Index replace a diagnosis?
No. The result is an informational estimate and does not constitute medical advice: always consult a healthcare professional.